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Increased Transcutaneous Oxygen Tension in the Skin Dorsum Over the Foot in Patients With Diabetic Foot Disease in Response to the Topical Use of an Emulsion of Hyperoxygenated Fatty Acids

¹ Unidad de Pie Diabético. Clínica Universitaria de Podología
² Universitary Podiatry Clinic College of Podiatric Universidad Complutense de Madrid
³ Universitary Podiatry Clinic College of Podiatric
⁴ Nurse Coordinator of the Multidisciplinary Ulcer Unit

^* To whom correspondence should be addressed. E-mail: diabetes{at}enf.ucm.es.

	Abstract

The aim of this study was to examine changes in the skin over the feet of patients with diabetic foot syndrome after local application of a product containing hyperoxygenated fatty acids (HOFAs) by measuring transcutaneous oxygen. In 64 patients, transcutaneous oxygen pressure (TcPo₂) was measured on days 0, 7, 30, 60, and 90 of the study. Foot skin dryness, shedding, and skin color were also assessed using a clinical score.The patients were grouped on the basis of initial levels of transcutaneous oxygen; group 1 comprised patients with TcPo₂ >30 mm Hg and group 2 comprised patients with TcPo₂ <30 mm Hg on the skin over the dorsum of the feet. Increases in local oxygenation values were observed at a local level in group 2 patients after 30 days of treatment. Skin trophism showed clinical improvement in all patients and these observations may be attributed to improved local microcirculation.

First published on October 13, 2009, doi:10.1177/1534734609346839

The International Journal of Lower Extremity Wounds 2009;8:187.

A more recent version of this article appeared on December 1, 2009


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