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A Clinical Investigation on the Characteristics and Outcomes of Treating Chronic Lower Extremity Wounds using the TissueTech Autograft SystemCattedra di Endocrinologia Università di Roma Tor Vergata, Rome, Italy, luigi.uccioli{at}uniroma2.it The application of tissue engineering technology to wound healing has resulted in the development of a number of "living skin equivalents." These have become a viable option in the treatment of chronic, nonhealing wounds. Such wounds present a major cost burden as well as increased morbidity and mortality. Unique among skin tissue engineering technology is the TissueTech autograft system, as it incorporates an autologous dermal substituteHyalograft® 3Dand an autologous epidermal replacement, Laserskin® autograft. Each includes a matrix of a hyaluronic acid ester to promote cellular migration and graft take.
Key Words: tissue engineering hyaluronan chronic lower extremity wounds leg ulcers diabetic foot ulcer pressure ulcer
The International Journal of Lower Extremity Wounds, Vol. 2, No. 3,
140-151 (2003) This article has been cited by other articles:
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