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The International Journal of Lower Extremity Wounds
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Cutaneous Tissue Engineering and Lower Extremity Wounds (Part 1)

Elena Boschi, PhD

Bianca Maria Longoni, MD

Division of General Surgery and Transplants, Department of Oncology, Transplants and Advanced Technologies

Marco Romanelli, MD

Department of Dermatology, University of Pisa, Italy

Franco Mosca, MD

Division of General Surgery and Transplants, Department of Oncology, Transplants and Advanced Technologies

Tissue-engineered skin is a novel therapeutic with which difficult-to-heal lower extremity wounds may be treated. Such skins are products of cutaneous tissue engineering that provide an alternative for autologous or allogeneic tissue transplantation, thereby avoiding problems associated with donor site availability, the risk of infection, and scarring. Recently developed tissue-engineered skin equivalents have shown to be superior in certain ways to compression therapy for refractory venous ulcers and acute wounds. These biologic products behave similarly to autografts.

Key Words: tissue engineering • skin substitutes • wound healing

The International Journal of Lower Extremity Wounds, Vol. 3, No. 2, 80-86 (2004)
DOI: 10.1177/1534734604265695
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This article has been cited by other articles:


Home page
 INT J LOW EXTREM WOUNDSHome page
D. Mathieu and R. Mani
A Review of the Clinical Significance of Tissue Hypoxia Measurements in Lower Extremity Wound Management
International Journal of Lower Extremity Wounds, December 1, 2007; 6(4): 273 - 283.
[Abstract] [PDF]


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