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The International Journal of Lower Extremity Wounds
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Infection in the Neuroischemic Foot

Michael Edmonds, MD, FRCP

King’s College Hospital, London, UK, michael.edmonds{at}kingsch.nhs.uk

Infection in the neuroischemic foot can lead to cellulitis, which often progresses to necrosis as a result of septic vasculitis. Therefore, it is important to diagnose infection early. However, the signs and symptoms of infection are diminished in the neuroischemic foot. Microbiological investigation is essential. Severe infection needs intravenous antibiotic therapy and urgent assessment of the need for surgical drainage and debridement. Infected neuroischemic feet need vascular assessment and intervention where appropriate. It is important to maintain strict metabolic control and optimize cardiovascular function. Recent modern approaches based on multi-disciplinary clinics have resulted in improved results in the management of infection in the ischemic diabetic foot.

Key Words: diabetic foot disease • infection • ischemia • neuropathy • neuroischemia • amputation

The International Journal of Lower Extremity Wounds, Vol. 4, No. 3, 145-153 (2005)
DOI: 10.1177/1534734605280597
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