This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Scopus Google Scholar Articles by Mulder, G. Articles by Lee, D. K. PubMed PubMed Citation Articles by Mulder, G. Articles by Lee, D. K. Social Bookmarking                         What's this?

Case Presentation: Xenograft Resistance to Protease Degradation in a Vasculitic Ulcer

University of California, San Diego, CA, USA, gmulder{at}ucsd.edu

Daniel K. Lee

University of California, San Diego, CA, USA

Vasculitic ulcers are related to numerous underlying etiologies including autoimmune disease, rheumatoid arthritis and other inflammatory conditions.The resulting ulcerations are associated with high levels of pain, inflammation and tissue necrosis. Current therapies, including surgical intervention, are limited by the underlying inflammatory process and complications secondary to the wound etiology. conservative care has been relatively unsuccessful in promoting wound closure.This case presentations reviews the successful results of using a xenograft in the treatment of an inflammatory ulcer associated with cryoglobulinemia and vasculitis. Product integrity was maintained postoperatively, compared to an allograft, thereby allowing the wound treatment site to progress to closure.The type of cross linkage of acellular grafts may have a direct effect on product stability and treatment outcomes.

Key Words: vasculitic ulcer • cryoglobulinemia • xenograft • allograft

The International Journal of Lower Extremity Wounds, Vol. 8, No. 3, 157-161 (2009)
DOI: 10.1177/1534734609344126


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?